Application of step response impedance spectroscopy for detection of skin irritation

This paper describes the application of a noninvasive electrical impedance method to evaluate skin irritation. The impedance method is based on a current response to a voltage step excitation. The skin irritation was induced on volar forearm of 20 subjects by sodium lauryl sulphate dissolved in distilled water at concentration of 5.0%. The impedance parameters obtained before the application of irritant and after its removal were statistically difference. The results showed that the impedance parameters can detect the presence of oedema induced by irritation.