Comparison of PCR with culture applied on nasopharyngeal and throat swab specimens for the detection of Bordetella pertussis
2011
AbstractAn in-house nested polymerase chain reaction (PCR) was prospectively compared with culture for Bordetella pertussis detection in 435 nasopharyngeal and/or throat swabs from 304 patients. One hundred specimens – 21% of nasopharyngeal swabs and 25% of throat swabs – were PCR- and/or culture-positive. Seventy percent of positive nasopharyngeal samples and 44% of positive throat samples were culture-positive.
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