ALMS1 (Alstrom Syndrome 1), a new interacting protein of NKCC2, regulates apical NKCC2 trafficking, urinary concentration and blood pressure

NaCl absorption by the Thick Ascending Limb (TAL) is mediated by the apical Na/K/2Cl cotransporter, NKCC2. Increased NKCC2 activity and apical trafficking are associated to hypertension. However, o...