Clinical Study on the Therapeutic Effect of Western Medicine in the Treatment of Pulmonary Tuberculosis Combined with Yiqi Ziyin Runfei Decoction

Objective: To observe the clinical curative effect of traditional Chinese and Western medicine treatment of pulmonary tuberculosis. Method: To divide randomly 100 cases of pulmonary tu- berculosis into two groups, 57 cases in treatment group and 43 cases in the control group. The two groups were given conventional anti-tuberculosis treatment; the treatment group was based on routine treatment with Yiqi Ziyin Runfei decoction for 6 months. During the treatment, the im- provement of clinical symptoms, the negative conversion of sputum, diminished cavity and lesions absorption rate will be observed. Two groups were observed before and after treatment about level changes of peripheral blood IFN-γ (γ-interferon), interleukin 13 (IL-13), tumor necrosis fac- tor (TNF), hyaluronic acid (HA), and the situation of drug reaction improvement. Results: After 6 months of treatment in treatment group, the sputum negative conversion rate, diminished rate of cavity, lesions absorption rate, clinical symptom improvement rate were significantly better than that in the control group (P < 0.05), and the difference was statistically significant. After 6 months of treatment in two groups of patients, serum IL-13, IFN-γ levels increased with different degrees, and TNF, HA levels decreased compared with that before treatment (P < 0.05). The degree of in- crease, decrease in the treatment group was significantly better than that in the control group (P < 0.05), and the difference was statistically significant. As to the adverse drug reactions during the treatment (liver function damage, white blood cell decrease, gastrointestinal reaction, rash, ab- normal urine) in treatment group was obviously less than that in the control group (P < 0.05), and the difference was statistically significant. Conclusion: The clinical curative effect of pulmonary tuberculosis treatment combining traditional Chinese medicine with Western medicine is better than that with pure western medicine treatment. * 通讯作者。