Fetal growth retardation : associated malformations and chromosomal abnormalities

Objective: Our objective was to determine the incidence and pattern of chromosomal abormalities in fetal growth retardation. Study Design: Blood karyotyping was performed in 458 fetuses referred to us for further assessment of growth retardation at 17 to 39 weeks' gestation. Results: The fetal karyotype was normal in 369 and abnormal in 89 (19%) of the cases. The most common chromosomal defect in the group referred at Conclusion: The findings of the different types of chromosomal abnormalities and their ultrasonographically detectable phenotypic expression provide the background for prospective studies to determine the incidence of chromosomal abnormalities in unselected populations of small-for-gestational-age fetuses.