Targeted Radiation Therapy Can Treat Myxomatous Cerebral Aneurysms

Abstract Background Neoplastic cerebral aneurysms are rare presentation of cardiac myxomas. The natural history of such aneurysms is not well understood and the optimal treatment strategy remains unclear. Clipping and coiling are effective, though can carry significant morbidity. Chemotherapy and radiation can theoretically be effective though their clinical efficacy remains to be proven. Case Description Here we describe a patient with cardiac myxoma presenting with multiple progressively fusiform aneurysms. These aneurysms were noted to be growing during conservatively monitored given the eloquent location. Subsequently, the patient underwent multiple sessions of targeted radiation therapy which lead to obliteration, shrinkage or halting in growth of these aneurysms. Conclusion Low dose targeted radiation therapy can be safe and effective in treatment of neoplastic myxomatous aneurysms.