Prenatal Screening for Fetal Aneuploidy

Traditional prenatal diagnostic tests for fetal chromosomal abnormalities involve the risk of miscarriage. Therefore, to reduce this risk, noninvasive prenatal screening methods have been developed and have improved the detection rates of fetal aneuploidies. Recently, noninvasive prenatal testing (NIPT) was developed, resulting in a fetal aneuploidy detection rate >99% and achieving unparalleled precision as compared with previous prenatal screening methods. Therefore, NIPT has steadily reduced the number of invasive prenatal screens performed.