Electrochemical hydroxyapatite-cobalt ferrite nanocomposite coatings as well hyperthermia treatment of cancer

Abstract The fabrication of hydroxyapatite-Co-ferrite nanocomposite coatings was performed on stainless steel by chronoamperometry technique. HA-CoFe 2 O 4 nanocomposite films were characterized using X-ray diffraction, scanning electron microscopy, and vibrating sample magnetometer (VSM). The results reveal that CoFe 2 O 4 nanoparticles dispersed within the HA matrix have flake and strip shapes. The magnetic property of the nanocomposite was increased by increasing the concentration of CoFe 2 O 4 and a good saturation magnetization value was found to be 20.6 emu/g with 50% CoFe 2 O 4 . By comparing with pure CoFe 2 O 4 , the composite still retain moderate magnetization as well as its biocompatible characters. The specific absorption rate (SAR) values were altered according to the change in CoFe 2 O 4 concentration and the maximum SAR value was 125 W/g. The incorporation of CoFe 2 O 4 nanoparticles with HA coating was increased the corrosion resistance of HA in simulated body fluid (SBF). The results indicated that HA-CoFe 2 O 4 nanocomposite coating could be a promising surface treatment technique for stainless steel medical implants as well hyperthermia treatment of cancer.