A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis

Jeremy M. Shefner,Merit Cudkowicz,Orla Hardiman,Bettina M. Cockroft,Jacqueline H. Lee,Fady I. Malik,Lisa Meng,Stacy A. Rudnicki,Andrew A. Wolff,Jinsy Andrews

A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis

2019

Jeremy M. Shefner
Merit Cudkowicz
Orla Hardiman
Bettina M. Cockroft
Jacqueline H. Lee
Fady I. Malik
Lisa Meng
Stacy A. Rudnicki
Andrew A. Wolff
Jinsy Andrews

AbstractObjective: To assess the efficacy of tirasemtiv, a fast skeletal muscle troponin activator, vs. placebo in patients with amyotrophic lateral sclerosis. Methods: VITALITY-ALS (NCT02496767) w...

Keywords:

Physical therapy
Medicine
Tirasemtiv
Amyotrophic lateral sclerosis
Physical medicine and rehabilitation
Placebo
clinical neurology
in patient
Randomized controlled trial
Skeletal muscle
Troponin
Anesthesia

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