Advances in Early Detection and Diagnostic Adjuncts in Oral Cavity Cancer

Oral and pharyngeal cancers combined rank within the top ten most common malignancies in the world for men, with an estimated global incidence of oral cancer alone at approximately 275,000 [1]. Over 90 % of oral cancers affecting the lips, gingiva, tongue, buccal mucosa, floor of mouth and hard palate arise from the squamous epithelium and are thus termed oral squamous cell carcinomas (OSCCs) [2, 3]. Conversely, neoplasms originating from the epithelial lining of oropharynx are called oropharyngeal squamous cell carcinomas (OPSCCs) [1].