A case of chronic necrotizing pulmonary aspergillosis due to Aspergillus flavipes associated with pulmonary fibrosis

1999 
: The patient was a 76-year-old man with complaints of fever, productive cough, and purulent sputum. He was on home oxygen therapy for pulmonary fibrosis. Antibiotics were administered, but with no improvement. Because the inflammatory condition persisted, the patient was admitted. Computed tomographic (CT) scans of the chest demonstrated infiltrative shadows and a fungus ball, and pulmonary aspergillosis was suspected. The patient was given an antimycotic agent and his symptoms gradually resolved. Subsequent chest CT scans revealed a reduction of the infiltrative shadows, but no reduction in the size of the fungus ball. Aspergillus flavipes was cultured from samples of bronchoalveolar lavage fluid. Aspergillus fumigatus is the most common causative agent of pulmonary aspergillosis. In this respect, our case was considered rare and of value to the diagnosis and treatment of future cases of pulmonary aspergillosis.
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