Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes

Ming Yang,Dandan Wei,Chunfen Mo,Jie Zhang,Xu Wang,Xiaojuan Han,Zhe Wang,Hengyi Xiao

Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes

2013

Ming Yang
Dandan Wei
Chunfen Mo
Jie Zhang
Xu Wang
Xiaojuan Han
Zhe Wang
Hengyi Xiao

Background Excessive circular fatty acid, particlarly saturated fatty acid, can result in insulin resistance in skeletal muscle, but other adverse effects of fatty acid accumulation in myocytes remain unclear.

Keywords:

Insulin resistance
Skeletal muscle
Myocyte
Endocrinology
Myokine
Clinical chemistry
Myogenesis
Diabetes mellitus
Internal medicine
Biology
Fatty acid
GLUT4
Glucose uptake
Gene expression
saturated fatty acid

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