Survey of factors associated with deep venous thrombosis after artificial liver treatment in patients with liver failure

Objective To survey the factors associated with deep venous thrombosis after artificial liver treatment in patients with liver failure. Methods A retrospective survey was used in our hospital from January 2014 to December 2016 consecutive liver failure patients by artificial liver treatment, collected patient data, including general demographic information, medical history. Results Medical history data were collected from 189 compliance cases, including deep venous thrombosis group (11 cases), no deep venous thrombosis group(178 cases), and 5.82%(11/189) of deep vein thrombosis. There were significant differences in age (χ2=7.17, P=0.027) , catheterization (χ2=4.99, P=0.025) , number of successful venipuncture (χ2=10.856, P=0.004) , artificial liver frequency (χ2=67.481, P<0.01) , activity status (χ2=9.607, P=0.022) , D-dimer (t=12.318, P<0.01) , infection (χ2=17.231, P=0.001) and other factors in thrombosis group and thrombus group (P <0.05). Logistic regression showed that age (OR=1.643, P=0.01) , activity status (OR=1.643, P=0.01) , number of successful venipuncture (OR=6.049, P<0.01) , D-dimer (OR=2.532, P=0.005) and infection (OR=2.463, P=0.008) were independent risk factors for thrombosis. Conclusions Deep vein thrombosis after artificial liver injury in liver failure is not uncommon, and the prevention of deep vein thrombosis after artificial liver surgery is strengthened, especially for elderly, absolute bed, venous puncture injury patients, elevated D-dimer and infected patients. Key words: Liver failure, acute; Liver, artificial; Venous thrombosis; Influencing factors