Effect of Rotary Instrument Mineral Oil Lubricant on Osseointegration: A Randomized, Blinded Study in Rabbits

The mechanisms of early failures in dental implant osseointegration are unclear. A possible cause of low levels of bone formation is implant contamination with lubricants during insertion. To explore the impact of lubricant contamination on dental implants, we used five New Zealand rabbits and inserted two implants per tibia in each animal for a total of four implants per animal (20 implants in total). In general, bicorticalization was achieved. The first implant was placed as suggested by the manufacturer with no lubricant used (control). The second implant was placed using a freshly lubricated contra-angle handpiece (test), which was used only for the test implants. Implant allocation was randomized, and the examining histologist was blinded to the results. All implants were placed by the same surgeon. The animals were maintained in accordance with animal experimentation guidelines. None of the implants failed to osseointegrate. Moreover, no significant difference was observed between the test and contr...