Effect Of Dexmedetomidine On Stress Response To Extubation

Laryngoscopy as well as tracheal intubation cause significant changes in the hemodynamics of the patient.(1).A similar set of hemodynamic derangements have been noticed by various workers during tracheal extubation(2).These responses may produce myocardial ischemia or infarction in susceptible patients. Various agents like lidocaine and esmolol have shown to attenuate these responses(3).Dexmedetomidine, an α2 agonist has been successfully used for attenuating the stress response to laryngoscopy.(4)We conducted a double blind study to examine the role of Dexmedetomidine on hemodynamic changes during extubation of trachea.