A CASE OF PLASMA CELL GRANULOMA OF THE STOMACH

Plasma cell granuloma is a granulomatous disorder of unknown origin that is histologically composed of plasma cell predominant cell infiltrate and fibrous connective tissue. This time we experienced a case of plasma cell granuloma arisen in the stomach. A 45-year-old man was admitted to the hospital because of appetite loss and epigastric pain. Gastric endoscopy revealed ulcerative lesion surrounded with irregular mucosa in the pyloric antrum. Biopsy yielded no definite diagnosis. Non-epithelial malignant tumor was suspected, and a gastrectomy was performed. Histopathologically, the difinite diagnosis of plasma cell granuloma was made. In this case, we were able to observe the morphological changes in ulcerative lesion of plasma cell granuloma with time. Domestic cases of gastric plasma cell granuloma are numbered only ten, and the clinical features of the disorder are still obscure. Some bibliographical comments in terms of the clinical features are also presented here.