Two new penterpenoid saponins and a new diterpenoid glycoside from Hemsleya chinensis

Two new penterpenoid saponins, hemsloside-Ma4 (1) hemsloside-Ma5 (2), and a new diterpenoid glycoside, hemsloside-Ma6 (3), were isolated from the rhizomes of Hemsleya chinensis. By detailed analysis of the NMR spectra and chemical methods, the structures of new compounds were determined to be 3-O-beta-L-arabinopyranosyl-(1 -> 3)-O-(6'-methyl ester)-beta-D-glucuropyranosyl-oleanolic acid-28-O-beta-D-glucopyranosyl-(1 -> 6)-O-beta-D-glucopyranoside (1), 3-O-beta-L-arabinopyranosyl-(1 -> 3)-O-(6'-methyl ester)-beta-D-glucuropyranosyl-oleanolic acid-28-O-beta-D-xylopyranosyl-(1 -> 6)-O-beta-D-glucopy-ranoside (2), and 13 epsilon-hydroxylabda-8(17), 14-dien-18-oic acid-18-O-alpha-L-rhamnopyranosyl-(1 -> 2)-O-beta-D-glucopyranosyl-(1 -> 4)-O-alpha-L-rhamnopyranoside (3). Diterpenoid-type compound (3) was isolated from Hemsleya genus for the first time. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.