Overview of Malignancy in Pregnancy

The incidence of cancer during pregnancy is increasing although it is relatively rare, which is expected to rise with an increase in the maternal age of the pregnancy. Due to the ambiguity of the symptoms, the diagnosis of cancer is often delayed. Diagnosis of cancer in pregnancy needs complex management issues that balance the benefit of treatment for the mother and harm for the fetus. Every patient should be personalized with a multidisciplinary system of obstetricians, gynecologists, oncologists, radiologists, and neonatal specialists and it should assist patients in making informed decisions about the best diagnosis and management for mother and fetus. Radiotherapy, chemotherapy, and surgery could be provided as a management option. In most cancer, pregnancy did not seem to have an adverse effect on maternal prognosis. In this article, we review various perspectives on the diagnosis and treatment of cancer during pregnancy as well as the prognosis of cancer in pregnancy.