Cohort profile: National Investigation of Birth Cohort in Korea study 2008 (NICKs-2008).
2021
Background An adequate large-scale pediatric cohort based on nationwide administrative data is lacking in Korea. Purpose This study established the National Investigation of Birth Cohort in Korea study 2008 (NICKs-2008) based on data from a nationwide population-based health screening program and data on healthcare utilization for children. Methods The NICKs-2008 study consisted of the Korean National Health Insurance System (NHIS) and the National Health Screening Program for Infants and Children (NHSPIC) databases comprising children born in 2008 (n = 469,248) and 2009 (n = 448,459) in the Republic of Korea. The NHIS database contains data on age, sex, residential area, income, healthcare utilization (International Classification of Diseases-10 codes, procedure codes, and drug classification codes), and healthcare providers. The NHSPIC consists of seven screening rounds. These screening sessions comprised physical examination, developmental screening (rounds 2-7), a general health questionnaire, and age-specific anticipatory guidance. Results During the 10-year follow-up, 2,718 children (0.3%) died, including more boys than girls (hazard ratio = 1.145, p < 0.001). A total of 848,048 children participated in at least one of the seven rounds of the NHSPIC, while 96,046 participated in all seven screening programs. A total of 823 infants (0.1%) weighed less than 1000 g, 3177 (0.4%) weighed 1000-1499 g, 37,166 (4.4%) weighed 1500-2499 g, 773,081 (91.4%) weighed 2500-4000 g, and 32,016 (5.1%) weighed over 4000 g. There were 23,404 (5.5%) premature babies in 2008 compared to 23,368 (5.6%) in 2009. The developmental screening test indicated appropriate development in 95-98% of children, follow-up requirements for 1-4% of children, and recommendations for further evaluation for 1% of children. Conclusion The NICKs-2008, which integrates data from the NHIS and NHSPIC databases, can be used to analyze disease onset prior to hospitalization based on information such as lifestyle, eating habits, and risk factors.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
35
References
3
Citations
NaN
KQI