The Boston type 1 keratoprosthesis and endophthalmitis: a systematic review

Substituting the natural cornea is no easy task. Researchers have shaped and honed methods for over 200 years, seeking the ultimate surrogate. Today the Boston type 1 keratoprosthesis is the world’s most commonly used artificial cornea. Advances in both surgical technique and postoperative management have drastically reduced the prevalence of endophthalmitis. The authors conducted a systematic review of endophthalmitis arising from the Boston type 1 technique. Medline, Embase, Google Scholar and The Cochrane Library were systematically searched alongside grey literature sources for relevant studies. Many methods are currently employed to reduce complications including vancomycin prophylaxis and the use of bandage contact lenses. The results will be presented with a view to collate the research conducted to date.