Quantification and evaluation of calcium, magnesium, strontium, copper,zinc and iron in samples oseas and serum sanguineo of patients withartrosis
2007
The levels by Spectroscopy of Atomic Absorption in Flame (EAA) of
calcium (Ca), magnesium (Mg), strontium (Sr) copper (Cu), zinc (Zn) and
iron (Fe) in bone and sanguineous samples were determined in 17
patients with clinical references of arthrosis. Arthrosis is a chronic
disease characterized by the wearing down and the progressive
degeneration of the intra articular cartilage loints, which causes
pain, loss of normal mobility and deformation. Although all the
structures you will articulate can be affected, the anatomical changes
are mainly located in the cartilage to articulate and the bone to
yuxtaarthicular. To grief that the arthrosis is commonest of the
rheumatic diseases, their pathogenesis perfectly is not clarified. It
could be a secondary affection to other diseases that cause to the
deterioration and the deformity to articulate, or to be originated by
repeated traumas you will articulate. It is known that its incidence is
increased with the advance of the age, and that the pathology differs
from those producers of other inflammatory rheumatic diseases, like for
example rheumatoid arthritis. Numerous works of investigation develop
new methods to study the cells, the chemistry and the function of the
cartilage, producing a fast development of our knowledge on the
arthrosis. The arthrosis to say itself then is a crystallization of the
bony weave by accumulation of Ca and Mg (at level of the cartilages or
cortical zone), specifically in the joints (calcification). Probably
the cortical one is presumed that the Ca, Sr and Mg pay attention to
some zone of the bone, producing the crystallization the Faith, is a
intrinsic component of the bony matrix., elements, mainly Ca, Sr, Mg
and Cu tend to migrate to the sanguineous torrent, conserving the
mechanism of homeostasis. The Zn, on the other hand showed its
antagonistic effect with the Cu. Being these results of a
cross-sectional study, such they are not conclusive. Single they
allowed observing the behavior of the different studied elements.. The
analyzed samples come from patient arthrosis submissive operations for
effects of prothesys or reconstruction of the bone damage. The analysis
of the results shows a close relationship between the content of these
elements, sex and the studied, being but marked pathology for Ca, Sr,
Mg and Cu. Our results are in agreement with previous reports showing
that Mg helps to fix Ca and Sr. helps bone reabsorption whereas a
deficit of Cu could be associated with bone alterations
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