Endolumenal endoscopic full-thickness resection of muscularis propria-originating gastric submucosal tumors.

Abstract Background: This study retrospectively reviewed 48 cases of gastric submucosal tumors (SMTs) treated by endolumenal endoscopic full-thickness resection (EFR) microsurgery in our gastrointestinal endoscopy center. Patients and Methods: From November 2009 to October 2012, 48 cases underwent endolumenal EFR for resection of muscularis propria–originating gastric SMTs. Characteristics of the 48 patients, clinical efficacy, safety of EFR, and post-EFR pathological diagnoses were evaluated retrospectively. Results: EFR was successfully performed in 48 cases with 52 lesions. The median operation time was 59.72 minutes (range, 30–270 minutes; standard deviation, 39.72 minutes). The mean tumor size was 1.59 cm (range, 0.50–4.80 cm; standard deviation, 1.01 cm). During the EFR process, dual-channel gastroscopy was applied in 20 cases of SMTs, and paracentesis during the EFR process was applied in 9 cases. EFR for larger SMTs and gastric corpus–originating SMTs had longer operative times. Pathological diagn...