Langerhans cells in labial minor salivary glands in primary Sjögren's syndrome

Langerhans cells were demonstrated among the mononuclear cells in inflamed labial minor salivary glands in a patient with primary SjOgren's syndrome. Langerhans cells were visualized by the monoclonal antibody, OKT6, by an indirect immunofluorescence technique. The possible role of Langerhans cells as antigen-presenting cells in diseased glandular tissue in primary SjOgren's syndrome must be further studied.