Pathobiology and Neuropathology of Meningiomas

The meninges include the dura mater, the arachnoi-dal cap cells and granulations, the subarachnoidal blood vessels and fibroblasts, and the pia. The changing composition of these histological elements is responsible for the different subtypes of meningiomas. Intraventricular meningiomas arise from the tela choroidea of the choroid plexus, hemangiopericytic meningiomas from mesenchymal perivascular cells or, in a different view, from men-ingothelial cells transformed into pericytes. Thus, meningiomas are tumors with both neuroectodermal and mesenchymal histogenesis [40, 101].