M30 and M65 assessments demonstrate pro-apoptotic effect of LBY135, a monoclonal antibody agonist to DR5

14587 Background: LBY135 is a chimeric (mouse/human) IgG1 monoclonal antibody agonist that binds with high specificity to the DR5 receptor and mimics the action of TRAIL. In a phase I trial, LBY135...