Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.

Venessa T. Chin,Adnan Nagrial,James R.W. Conway,Claire Vennin,Lorraine A. Chantrill,Angela Chou,Angela Steinmann,Anthony J. Gill,Jeremy Humprhis,Alison Drury,Danielle Froio,Ashleigh Morgan,Andrew V. Biankin,Paul Timpson,Marina Pajic

Effect of Rho/ROCK pathway inhibition on metastasis-free and overall survival in biomarker selected, orthotopic, patient-derived models of pancreatic cancer.

2017

Venessa T. Chin
Adnan Nagrial
James R.W. Conway
Claire Vennin
Lorraine A. Chantrill
Angela Chou
Angela Steinmann
Anthony J. Gill
Jeremy Humprhis
Alison Drury
Danielle Froio
Ashleigh Morgan
Andrew V. Biankin
Paul Timpson
Marina Pajic

e15759Background: PC is a highly lethal disease which metastasises early. The sequencing efforts of the Australian Pancreatic Cancer Genome Initiative (APGI) identified ROCK-1 as a target of intere...

Keywords:

Pancreatic cancer
Pathology
Metastasis
Cancer research
Biomarker (medicine)
Medicine
rho rock
overall survival
Genome
Disease

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