Cloning and Characterization of Goose PPARγ Gene Comparison with other Vertebrates

The peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor involved in the transcriptional control of energy, lipid, and glucose homeostasis. In this study, we cloned goose PPARγ gene. The amplified fragment contains coding region sequence with 1731 nucleotides, which putatively codes for 453 amino acids (AA). The homology of nucleotide sequences is from 81.4% to 99.9% among the twelve vertebrates, while the similarity of amino acid sequence ranged from 91.8% to 99.8%. Results showed that the PPARγ gene is conservative among different species. This work constructed the basis for further research on the molecular nature and genetic markers of PPARγ for metabolism traits in goose.