2019冠状病毒病首次核酸阴性与首次核酸阳性患者临床及CT影像学表现./ 2019冠状病毒病首次核酸阴性与首次核酸阳性患者临床及CT影像学表现./ Clinical and CT imaging features between the first nucleic acid - negative and first nucleic acid - positive COVID - 19 patients.

OBJECTIVES: To investigate the role of chest CT for the diagnostic work-up for patients with suspected infection of coronavirus disease 2019 (COVID-19). METHODS: The clinical data and imaging findings of the first nucleic acid-negative COVID-19 patients were analyzed and compared with the first nucleic acid-positive patients. RESULTS: Compared with the first nucleic acid-positive patients, the onset time of the first nucleic acid-negative patients was shorter [(3.58�2.94) d], but the diagnosis was longer [(3.92�3.66) d]. There were no significant differences in the characteristics of the clinical data and radiological findings between the 2 groups (P>0.05). CONCLUSION: Chest CT examination is important to avoid COVID-19 missed diagnosis due to false negative nucleic acid.