Analysis on effects of HAART from 377 Chinese AIDS

Aim: To seek the suitable method for elevating the effects of HAART and delaying the emergence of the resistance. Methods: 377 AIDS patients from the same area were divided into the full supervision ( n = 134) and non-full supervision ( n = 134) treatment groups. All the patients were given the same HAART traerment for 12 months. At 1,2,3, 6,9,12 months after treatment,the HIV-RNA load were detected by PCR ,CD4 + ,CD8 + T cells were detected by flow cy- tometry ,and white blood cell ( WBC) were detected by routine blood test. Results: The counts of CD4 + ,CD8 + T cells elevated in the two groups ,and there were no obviously different. The HIV-RNA load between the two groups were different ( F group = 3. 781,F time = 2. 561,F interaction = 352. 791,P 0. 05) ; Non-full supervision treatment group was higher than the full supervision treatment group at 6,9,12 months after treatment. Conclusion: The full supervision treatment could delay the emergence of resistance and prolong the effect of HAART.