A case of primary cutaneous diffuse large B-cell lymphoma, leg type

A case of primary cutaneous diffuse large B-cell lymphoma, leg type is reported. A 51-year-old patient presented with a 5-month history of multiple erythematous nodules on the right leg. Histopathologic examination revealed an acellular infiltration between the epidermis and dermis as well as dermal infiltrationwith large and atypical lymphoid cells which stained positive for CD20 (++), Bcl-6 (+), Bcl-2 (+), Pax-5 (+), Ki-67 (50％-75％+ ), C D79a (+) , MUM-1 ( + ) but negative for CD10. The patient was diagnosed with primary cutaneous large B-cell lymphoma, leg type and treated with anti-CD20 monoclonal antibody and CHOP regimen. Thereafter, his condition improved. Key words: Lymphoma, B-cell;  Skin