Nódulo umbilical metastático (nódulo da Irmã Maria José): um sinal de alerta para tumoração maligna intra-abdominal - relato de caso

The umbilical metastatic tumoral nodule, Sister Mary Joseph's nodule, is a rare clinical sign indicative of disseminated intra-abdominal tumor, and may be the first evidence of malignancy. The authors report a case of a patient with umbilical metastatic nodule in whom the diagnosis of the primary tumor was possible by immunohistochemistry of the lesion biopsy.