Comparison of Age and Gender Differences of Tryptophan Metabolites in Patients of Major Monopolar and Bipolar Depression
2020
Background: No research has been done for the determination of
plasma levels of tryptophan metabolites in patients of monopolar and bipolar
depression. Methods: Ultra high-speed liquid chromatography/mass
spectrometry has been used for the simultaneous determination of plasma levels
of tryptophan metabolites in depressive patients. Results: No significant age and gender differences were
shown in monopolar depressive patients and some differences were shown in
bipolar patients. The administration of drugs such as antidepressants,
antipsychotics, mood stabilizers do not seem to have affected the results. Conclusion: In patients of major monopolar depression age and gender differences of
plasma levels of tryptophan metabolites disappear although significant
differences are observed in healthy volunteers. Some differences of age and
gender differences were shown between monopolar and bipolar depressive
patients.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI