Re-activation of IPF and Appearance of Cancer on the Native Lung afterSingle Lung Transplantation

IPF is an interstitial pneumonia of unknown origin with a very bad prognosis. A universally accepted therapeutic approach has still not been elaborated. Lung transplantation represents in many cases the only possible therapy for these patients. This report describes a case of IPF treated by lung transplantation. Radiological follow up of the patient after immunosuppressive therapy showed a re-activation of the primitive pathology on the native lung, a possible relapse of IPF on the graft and the appearance of two neoplastic lesions, one in the native lung and one in the left maxillary sinus.