Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy

Background:Little is known about the prevalence and pattern of hepatitis B virus (HBV) mutations in HIV/HBV co-infected individuals on long-term lamivudine (3TC) therapy.Methods:HBV polymerase/envelope/basal core promoter/pre-core sequences from 81 HIV–HBV co-infected persons who received at least 6