The Role of the Multi Inflammatory Index as a Novel Inflammation-Related Index in the Differential Diagnosis of Massive and Non-massive Pulmonary Embolism.

OBJECTIVE Systemic inflammatory response and pro-coagulator factors are critical in acute pulmonary embolism. Recently, there is increasing evidence that the multi inflammatory index (MII) may be prognostic in many clinical situations. The study investigated whether MII-1 and MII-2 can distinguish massive (MPE) and non-massive pulmonary embolism (NMPE). METHODS A total of 146 patients (72 MPE and 72 NMPE) were included in the study that was designed as a retrospective cross-sectional analysis. Following hemogram analysis, MII-1 (platelet-to-lymphocyte x CRP) and MII-2 (neutrophil-to-lymphocyte x CRP) were calculated manually. RESULTS MII-1 and 2 showed a positive significant correlation with PLR and NLR, moderate positive correlation with CPR, and weak positive correlation with PAP (p 0.05). CONCLUSION Although MII-1 and MII-2 are simple, cheap, and easy indexes to calculate, they showed a strong ability to distinguish MPE and NMPE compared to the previously studied classical inflammatory indexes.