Probable Mode of Action of Sanjivani Vati - A Critical Review

Mode of action of a poly herbal Ayurvedic formulation is a critical and essential issue to be considered in assuring the therapeutic efficacy and safety. Sanjivani Vati is one of the commonly used preparation containing very safe and easily available Herbal drugs. It is first mentioned in Sharangdhara Samhita and used in Jwara (Fever), Visuchika (Gastro-enteritis), Gulma (Painful abdominal lump), Ajirna (Indigestion) and Sarpadamsa (Snake bite). This Ayurvedic formulation is commonly practiced to treat various gastrointestinal disorders mainly arises from Mandagni and Mandagni leads to Ama (Undigested Food Residue) formation in the body. Drugs present in Sanjivani Vati mainly of Katu, Tikta Rasa, Laghu, Tikshana, Ruksha Guna, Usna Virya, Madhura Vipaka, Deepana, Pachana, Anulomana, Rochana, Shoolhara, Krimighna, Jwaraghna, Triptighna, Vishaghna properties and have Kapha-Vata hara action, which improves the Jatharagni by relieving Ama. So Sanjivani Vati shows Amahara action (expels metabolites and detoxifies the system) which can cure diseases which are derived due to Mandagni (Digestive impairment) like Ajirna, Visuchika, Gulma, Jwara. The present study is aimed to critically review the formulation ingredients and probable mode of action of Sanjivani Vati in different clinical conditions.