Intermittent high-spiking fever, muscle and joint pain with sudden chest pain: Adult-onset still's disease?

Adult-onset Still's disease (AOSD) is a clinical syndrome characterized by long-term intermittent fever, transient polymorphic rash, arthritis or arthralgia, pharyngalgia, and accompanied by systemic involvements. The pathophysiology of AOSD has recently been classified as a complex autoinflammatory disease. Sometimes it is necessary to differentiate from coronary heart disease. In recent years, anakinra has been used to treat AOSD with promising results.