A phase 2 basket trial of combination therapy with trastuzumab and pertuzumab in patients with solid cancers harboring HER2 amplification (JUPITER trial).

Ryo Kudo,Toshio Kubo,Yukiko Mori,Yohei Harada,Hidekazu Shirota,Hideyuki Hayashi,Masayuki Kano,Yasushi Shimizu,Eri Ishibashi,Hirotoshi Akita,Hisahiro Matsubara,Hiroshi Nishihara,Chikashi Ishioka,Naoko Sueoka-Aragane,Manabu Muto,Shinichi Toyooka,Ukihide Tateishi,Akihiro Hirakawa,Satoshi Miyake,Sadakatsu Ikeda

A phase 2 basket trial of combination therapy with trastuzumab and pertuzumab in patients with solid cancers harboring HER2 amplification (JUPITER trial).

2021

TPS3141Background: The human epidermal growth factor receptor 2 (HER2) gene amplification and mutations have emerged as oncogenic drivers and therapeutic targets not limited to breast and gastric c...

Keywords:

in patient
Cancer research
Pertuzumab
Medicine
HER2 Amplification
Human Epidermal Growth Factor Receptor 2
Trastuzumab
Gene duplication
Combination therapy
JUPITER trial

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