O014. The diagnostic mistake: when the patient reports pain affecting eyes and benzodiazepines abuse without any glaucoma or any apparent organic cause

Background It is not so infrequent that a patient reports severe pain with a clear focus in/around the eye that looks like an atypical facial pain/persistent idiopathic facial pain. All the patients fulfilled DMS-IV criteria for depression or bipolar disorder-I and sleep and benzodiazepines overuse were reported as the only escape and cure treatment. This may or may not appear as a psychological flight reaction characterized by vegetative signs [1], or a medication-overuse headache. The diagnosis could be wrong even though the IHS/IASP and psychological criteria were respected. What could be the problem? We did not take into account that demodex is present even in man. Demodex -type A and type B-, the most serious non-neoplastic dermatological disease [2,3], is not so widely known in human pathology [4]. This ascaris provokes discomfort and pain, the severity of which depends on the extent and seriousness of the disease [2-4], as well as on the pain proneness evidenced in third hyperalgesia test we proved several years ago [5]. Thus, pain proneness and pain redundancy might be present in both migraine sufferers and in their relatives.