Anaesthetic and cardiopulmonary evaluation following xylazine-Diazepam-ketamine-propofol administration with or without local infiltration analgesia using mepivacaine during inguinal castration in Donkeys

The present study was performed to investigate the cardiopulmonary responses and hypoalgesic efficacy of diazepam/ketamine anaesthesia induction followed by xylazine-propofol infusion alone (XDKP) or with a local infiltration of mepivacaine (XDKPM) for inguinal castration in donkeys. A 10 male adult donkeys were assigned to two groups (XDKP and XDKPM). Donkeys were sedated by xylazine then anaesthesia was inducted with followed by diazepam/ketamine. Anaesthesia was maintained by propofol infusion 0.1 mg/kg/h. XDKPM group, mepivacaine 2% were locally infiltrated on each side and two min before surgical incision. Both group got smooth induction and recovery. The pain scale scores showed a significant higher compared to baseline in both groups. In conclusion, a combination of XDKP is balanced total intravenous anaesthesia regimen with cardiopulmonary stability in donkeys undergoing inguinal castration. Keywords: xylazine, propofol, mepivacaine, inguinal castration, donkey