Correlation of BODE index with extrapulmonary comorbidities of COPD patients

2014 
Introduction : COPD patients show features of systemic inflammation. They are the result of a systemic "spill-over" of the inflammatory and repairatory events in the lungs. The components of this systemic inflammation account for the extrapulmonary manifestations of COPD. Aims and objectives : To study the correlation between BODE index and extrapulmonary comorbidities of COPD. Methods : 100 patients who presented to respiratory medicine outpatient department with complains of breathlessnesss, cough or sputum production and history of exposure to risk factors were enrolled for the study. After diagnosing and analysing the severity of COPD based on BODE index score patients were screened for extrapulmonary comorbidities- hypertension, heart failure, ischemic heart disease, diabetes mellitus, dyslipidemia, anxiety, depression, osteoporosis, nutritional, anemia,polycythemia, microalbuminuria, and chronic kidney disease started on treatment and followed up after 1 yr. Results : Hypertension was the most common comorbidity present in 58%, followed by nutritional and osteoporosis in 44%. There was significant statistical correlation (p value Conclusion : BODE index - a simple effective and valid scoring system in analysing the overall severity of COPD should be used routinely for optimal management of patients.
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