Search for a Synergism with Different Drugs in the Field of Antiviral Chemotherapy

Additional findings about the synergism between Rec. 15/0209 and Amantadine are reported. While it is clearly demonstrable in embryonated and de-embryonated chicken eggs by measuring both virus titer and virus RNA synthesis of CAM suspensions, the results are much less constant in the embryonated eggs by measuring HA in the allantoic fluids and over all in the mice. The implications arising from these results are discussed.