Mikrofluidische Einzelzelluntersuchungen mikrobieller Interaktionen

Interspecies interactions inside microbial communities bear a tremendous diversity of complex chemical processes that are by far not understood. For the investigation of these interactions, precise analytical tools are often missing. This article presents microfluidic single-cell tools that can be used for dynamic growth analysis of contact-based (here: horizontal gene transfer) and contact free (diffusive) interactions (here: L-lysine exchange) between microbial cells and colonies on single-cell level.