Comparison of Chest CT images between Confirmed and Suspected Cases of COVID-19/ 新型冠状病毒肺炎确诊与疑似患者的临床和胸部CT影像比较

Objective: To explore the value of chest CT features and clinical indexes in the differential diagnosis between suspected COVID-19 with two or more negative nucleic acid tests and confirmed COVID-19 Methods: The clinical data and chest CT images of 105 cases withconfirmedCOVID-19 (55 males and 50 females, aged from 2 month to 88 years) and 97 cases with suspected COVID-19(59 males and 38 females, aged from 1 month to 93 years) were analyzed retrospectively in Shiyan Taihe Hospital from January 21 to February 10, 2020 χ2test and two independent sample t test were used to analyze the clinical data and CT signs of the two cases, with P<0 05 for the difference statistically significant Results: Compared with the suspected patients, the average age of diagnosis of covid-19 was higher (t = 2 460, P = 0 01) The main pathological changes were pure ground glass (68 cases) and mixed ground glass density (53 cases) (χ2 = 50 016, P< 0 01) Interstitial thickening (83 cases) (χ2 = 55 395, P< 0 01), vascular thickening (73 cases) (χ2 = 57 527, P< 0 01), air bronchoscopic sign or bronchiectasis Zhang (67 cases) (χ2 = 17 899, P< 0 01), cord focus (54 cases) (χ2 = 5 500, P = 0 02), easily distributed under the pleura and the long axis of the lesion was parallel to the pleura (89 cases) (χ2 = 23 597, P< 0 01), most of them had no pleural effusion (χ2 = 7 017, P< 0 01);both lesions were mainly distributed in patches (89 cases were confirmed, 87 suspected) (χ2 = 19 573, P< 0 01) In addition, the lesions of patients with confirmed covid-19 showed progress in short term (72 / 87, 82 76%), and those with suspected covid-19 showed remission in short term (63 / 89, 70 78%) The difference was statistically significant (χ2 = 51 114, P< 0 01) There was no significant difference in gender and distribution of pulmonary lobes (χ2 = 1 462, P= 0 23;χ2 = 7 381, P= 0 19) The number of white blood cells (χ2 = 17 891, P< 0 01) and the percentage of lymphocytes (χ2 = 11 151,P< 0 01) of covid-19 were mostly normal or decreased, creatine kinase (χ2 = 9 589, P< 0 01) were mostly normal, and erythrocyte sedimentation rate was mostly normal or increased (χ2 = 4 240, P= 0 04) Conclusions: The imaging features and biochemical indexes of diagnosed COVID-19 are different from those of suspected COVID-19 The comparative analysis of imaging features, clinical indexes and reexamination are helpful for the differential diagnosis of COVID-19 and suspected COVID-19