Primary Neuroendocrine Carcinoma of Breast: an uncommon variant.

Neuroendocrine carcinoma of breast ( NECB) is an aggressive variant of invasive mammary carcinoma. Very few cases of Primary NECB have been reported in the literature .  Here we report a 50 year female presented with left breast lump measuring 15 x 12 cm. of gradual onset with left axillary lymphadenopathy. On fine needle aspiration cytology of breast and lymphnode were positive for malignant cells. On ultrasonography of abdomino- pelvis showed metastasis to liver, peri  pancreatic and para aortic lymph nodes with minimal ascites. On histopathology reported as Primary NECB-Large cell type-left breast. We are presenting this case for its extreme rarity and aggressive clinical behaviour.  DOI: 10.21276/APALM.1094