A clinical case study on short term visual outcome of optic neuritis with IV Methyl prednisolone

This study conducted over 3 years (2013 to 2015) of time, in neurology department, in government general hospital , Kurnool.30 patients were studiedto evaluate the clinical profile and response to treatmentwith IV Methylprednisolone in  patientsof optic neuritis.patients were examined and investigated  and treated with IV methylprednisolone for period of 5 days and status of vision assessed after 6 to 8 weeks.  Among the 30 patients males were 13(43.3%) and females were 17(56.6%) in the age group of 12 to 65 years, complete visual loss is seen in 4 (13.3%) and partial visual loss is seen in 26(86.6%),unilateral involvement is seen in 18 (60%) and bilateral involvement is seen in 12 (40%) and fundus was normal in 19 (63.3%) ,hyperemia of optic nerve head and other changes were seen in 11 (36.7%). Prolonged p100 was the most commonly found abnormality on VEP which was seen in 19(65.5%) and absent wave was found in 10(34.4%).MRI was done in 13 patients out of which 8(61.5%) patients had normal MRI and 5 (38.4%) had abnormal findings. This study concluded that a Significant visual improvement is seen in 16(53.3%) and minimal improvement is seen in 14(46.7%) patients receiving IV Methylprednisolone consecutively for 5 days at  4 to 6 weeks.