Abstract P091: New Rho-kinase Inhibitors Reduce Cardiac Dysfunction And Vascular Remodeling In Pulmonary Hypertension In Rats

Tadeu L Montagnoli,Jaqueline da Silva,Bruna de Souza Rocha,Marina M. Silva,Bianca Santos-Carlos,Carlos A.M. Fraga,Gisele Zapata Sudo

Abstract P091: New Rho-kinase Inhibitors Reduce Cardiac Dysfunction And Vascular Remodeling In Pulmonary Hypertension In Rats

2020

Tadeu L Montagnoli
Jaqueline da Silva
Bruna de Souza Rocha
Marina M. Silva
Bianca Santos-Carlos
Carlos A.M. Fraga
Gisele Zapata Sudo

Pulmonary hypertension (PH) is characterized by extensive pulmonary vascular remodeling, leading to right ventricle (RV) hypertrophy and dysfunction. Since Rho kinases (ROCK) play a key role in smo...

Keywords:

Internal medicine
Pulmonary hypertension
cardiac dysfunction
Cardiology
Rho-associated protein kinase
Medicine

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