Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay

Katherine Clifton,Thereasa A. Rich,Christine Megerdichian Parseghian,Victoria M. Raymond,Arvind Dasari,Allan Andresson Lima Pereira,Jason Willis,Jonathan M. Loree,Todd Michael Bauer,Young Kwang Chae,Gary Bradley Sherrill,Paul Fanta,Axel Grothey,Andrew Eugene Hendifar,David H. Henry,Daruka Mahadevan,M. A. Nezami,Benjamin R. Tan,Zev A. Wainberg,Richard B. Lanman,Scott Kopetz,Van Karlyle Morris

Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay

2019

PURPOSEGene fusions are established oncogenic drivers and emerging therapeutic targets in advanced colorectal cancer. This study aimed to detail the frequencies and clinicopathological features of ...

Keywords:

Cancer research
Colorectal cancer
Medicine
Circulating tumor DNA
advanced colorectal cancer
clinicopathological features

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