Tromboză venoasă profundă la un prematur târziu - prezentare de caz

Renal vein thrombosis is the most frequent unrelated to vascular catheters thrombosis, with the highest incidence in the neonatal period. Risk factors include shock, dehydration, perinatal asphyxia, polycythemia, cyanotic heart disease, sepsis, maternal diabetes, traumatic births. There are few literature data regarding inherited prothrombotic anomalies. We report a premature newborn’s case, 36 weeks gestational age, of thrombophilic mother, who developed in the first 48 hours postnatally jaundice and thrombocytopenia, then hematuria and a mass in the left flank. Doppler ultrasound revealed left renal vein thrombosis. Despite heparin treatment, the thrombotic process extended. Factor V (Leiden) mutation was identified. Conclusions. Although infants with this presentation are typically treated with anticoagulants, there is a lack of evidence-based guidelines. A case-control study is required to investigate whether maternal prothrombotic disorders may be a risk factor for neonatal thrombotic processes.