Acute Liver Failure Following One Year of Daily Consumption of a Sugar-Free Energy Drink

We report a 36-year-old man who presented with 1 week of right upper quadrant abdominal pain, jaundice, and fatigue. He consumed 3 sugar-free energy drinks daily for the past year with binge alcohol use. His liver function progressively deteriorated, requiring orthotopic liver transplantation. Submassive hepatic necrosis with eosinophilic infiltrate was seen on pathology, consistent with drug-induced liver injury. Further investigation is warranted into identifying which individuals are susceptible to liver failure from energy drink consumption.